Effect of Rice Bran Oil on Cholesterol and Triglycerides in Patients with Central Obesity in the Working Area Health Centers Mattombong Pinrang
Main Article Content
Abstract
Poor metabolic effects on blood pressure, cholesterol, triglycerides, and insulin resistance are caused by being overweight or obese. The study's objective was to evaluate how rice bran oil affected the central obese patient's changes in triglycerides and cholesterol. The study was a quasi-experiment with a control group and a non-randomized pre- and post-test. Purposive sampling was used to choose the sample, which included 46 individuals split into two groups. For 15 days, the treatment group received 25 milliliters of rice bran oil each day, while the control group did not receive any. Triglyceride and cholesterol levels were assessed both before and after the intervention. Using the SPSS software, the data were examined by comparing the lipid profile results before and after a particular intervention using the Wilcoxon paired t test and comparing the treatment between groups using the Man Whithney independent t test. The study's findings show that the intervention group's cholesterol levels significantly changed, with an average drop of 13.39 mg/dl and an average increase of 8.39 mg/dl in the control group. The difference between the two groups is not statistically significant (p=0.144). This indicates that the intervention group and the control group are identical. There is an insignificant difference between the intervention group and control group (p=0.001), with the intervention group experiencing a considerable drop in triglyceride levels (mean decrease of 70.95 mg/dl) and the control group experiencing an increase of 10.73 mg/dl. This indicates that the intervention group and the control group are different.
Article Details
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
References
Borrell, L. N., & Samuel, L. (2014). Body mass index categories and mortality risk in US adults: the effect of overweight and obesity on advancing death. American journal of public health, 104(3), 512-519.
Cicero, A. F., Fogacci, F., Veronesi, M., Strocchi, E., Grandi, E., Rizzoli, E., ... & Borghi, C. (2020). A randomized placebo-controlled clinical trial to evaluate the medium-term effects of oat fibers on human health: the beta-glucan effects on lipid profile, glycemia and intestinal health (BELT) study. Nutrients, 12(3), 686. https://doi.org/10.3390/nu12030686
Durazo-Arvizu, R. A., McGee, D. L., Cooper, R. S., Liao, Y., & Luke, A. (1998). Mortality and optimal body mass index in a sample of the US population. American journal of epidemiology, 147(8), 739-749. https://doi.org/10.1093/oxfordjournals.aje.a009518
Ferrannini, E., Balkau, B., Coppack, S. W., Dekker, J. M., Mari, A., Nolan, J., ... & Beck-Nielsen, H. (2007). Insulin resistance, insulin response, and obesity as indicators of metabolic risk. The Journal of Clinical Endocrinology & Metabolism, 92(8), 2885-2892. https://doi.org/10.1210/jc.2007-0334
Flegal, K. M., Kit, B. K., Orpana, H., & Graubard, B. I. (2013). Association of all-cause mortality with overweight and obesity using standard body mass index categories: a systematic review and meta-analysis. Jama, 309(1), 71-82. https://doi.org/10.1001/jama.2012.113905
Goufo, P., & Trindade, H. (2014). Rice antioxidants: phenolic acids, flavonoids, anthocyanins, proanthocyanidins, tocopherols, tocotrienols, γ‐oryzanol, and phytic acid. Food science & nutrition, 2(2), 75-104. https://doi.org/10.1002/fsn3.86
Gregg, E. W., Cheng, Y. J., Cadwell, B. L., Imperatore, G., Williams, D. E., Flegal, K. M., ... & Williamson, D. F. (2005). Secular trends in cardiovascular disease risk factors according to body mass index in US adults. Jama, 293(15), 1868-1874.
Hendren, N. S., De Lemos, J. A., Ayers, C., Das, S. R., Rao, A., Carter, S., ... & Grodin, J. L. (2021). Association of body mass index and age with morbidity and mortality in patients hospitalized with COVID-19: results from the American Heart Association COVID-19 Cardiovascular Disease Registry. Circulation, 143(2), 135-144. https://doi.org/10.1161/CIRCULATIONAHA.120.051936
Kang, I. S., & Kong, K. A. (2021). Body mass index and severity/fatality from coronavirus disease 2019: A nationwide epidemiological study in Korea. PloS one, 16(6), e0253640. https://doi.org/10.1371/journal.pone.0253640
Meigs, J. B., Wilson, P. W., Fox, C. S., Vasan, R. S., Nathan, D. M., Sullivan, L. M., & D’Agostino, R. B. (2006). Body mass index, metabolic syndrome, and risk of type 2 diabetes or cardiovascular disease. The Journal of Clinical Endocrinology & Metabolism, 91(8), 2906-2912. https://doi.org/10.1210/jc.2006-0594
Mohajan, D., & Mohajan, H. K. (2023). Obesity and its related diseases: a new escalating alarming in global health. Journal of Innovations in Medical Research, 2(3), 12-23.
Mohammadshahi, J., Ghobadi, H., Matinfar, G., Boskabady, M. H., & Aslani, M. R. (2023). Role of Lipid Profile and Its Relative Ratios (Cholesterol/HDL‐C, Triglyceride/HDL‐C, LDL‐C/HDL‐C, WBC/HDL‐C, and FBG/HDL‐C) on Admission Predicts In‐Hospital Mortality COVID‐19. Journal of Lipids, 2023(1), 6329873. https://doi.org/10.1155/2023/6329873
Nie, Y., Luo, F., Wang, L., Yang, T., Shi, L., Li, X., ... & Lin, Q. (2017). Anti-hyperlipidemic effect of rice bran polysaccharide and its potential mechanism in high-fat diet mice. Food & Function, 8(11), 4028-4041.
Park, S., Chang, H. C., & Lee, J. J. (2021). Rice bran fermented with kimchi-derived lactic acid bacteria prevents metabolic complications in mice on a high-fat and-cholesterol diet. Foods, 10(7), 1501. https://doi.org/10.3390/foods10071501
Patimang, K. P. (2023). Hubungan Faktor Risiko pada Penderita Diabetes Melitus Tipe 2 Dengan Kejadian Penyakit Jantung Koroner di Pusat Jantung Koroner RSUP Dr. Wahidin Sudirohusodo (Doctoral dissertation, Universitas Hasanuddin).
Rashid, S., & Genest, J. (2007). Effect of obesity on high‐density lipoprotein metabolism. Obesity, 15(12), 2875-2888. https://doi.org/10.1038/oby.2007.342
Saphyakhajorn, W., Sirirat, R., & Sapwarobol, S. (2022). Effect of defatted rice bran supplementation on metabolic parameters and inflammatory status in overweight/obese adults with hypercholesterolemia: a randomized, placebo-controlled intervention. BMC nutrition, 8(1), 94. https://doi.org/10.1186/s40795-022-00586-9
Shaper, A. G., Wannamethee, S. G., & Walker, M. (1997). Body weight: implications for the prevention of coronary heart disease, stroke, and diabetes mellitus in a cohort study of middle aged men. Bmj, 314(7090), 1311. https://doi.org/10.1136/bmj.314.7090.1311
Sultani, R., Tong, D. C., Peverelle, M., Lee, Y. S., Baradi, A., & Wilson, A. M. (2020). Elevated triglycerides to high-density lipoprotein cholesterol (TG/HDL-C) ratio predicts long-term mortality in high-risk patients. Heart, Lung and Circulation, 29(3), 414-421. https://doi.org/10.1016/j.hlc.2019.03.019
Xie, C., Wen, P., Su, J., Li, Q., Ren, Y., Liu, Y., ... & Ren, J. (2019). Elevated serum triglyceride and low-density lipoprotein cholesterol promotes the formation of colorectal polyps. BMC gastroenterology, 19(1), 195. https://doi.org/10.1186/s12876-019-1115-9